Dr. Daniel Spitzer


Lab: 2224.02.125

Office: 2224.02.135

Phone: 39-23873


Research Topic:

Kinetically controlled redox-responsive supramolecular polymers
and triple helical assemblies in water

Curriculum Vitae:

11/2014 - 05/2018 Ph.D. student in the group of Prof. Pol Besenius, JGU Mainz
04/2014 - 09/2014 Masterthesis in the group of Prof. Pol Besenius, WWU Münster
08/2013 - 11/2013 Research project in the group Prof. Guillermo C. Bazan,
University of California Santa Barbara, USA
2012 - 2014 Master of Science in Chemistry, WWU Münster
2012 Bachelorthesis in the group of Prof. Armido Studer, WWU Münster
2009 - 2012 Bachelor of Science in Chemistry, WWU Münster
2008 Abitur, Gymnasium August-Dicke-Schule, Solingen



[19] Predicting the Supramolecular Assembly of Amphiphilic Peptides from Comprehensive Coarse-Grained Simulations.
S. Chakraborty§, C.M. Berač§, M. Urschbach, D. Spitzer, M. Mezger, P. Besenius, T. Speck*,
ACS Appl. Polym. Mater. 2022, 4, 822-831. DOI: 10.1021/acsapm.1c01208.
(§ these authors contributed equally)

[18] Lipid Bilayer Interactions of Peptidic Supramolecular Polymers and the Impact on Membrane Permeability and Stability.
S. Pannwitt, J. Kaltbeitzel, P. Ahlers, D. Spitzer, N. Hellmann, F. Depoix, P. Besenius, D. Schneider*,
Biochemistry 2020, 59, 1845-1853. DOI: 10.1021/acs.biochem.0c00114.

[17] Supramolecular Copolymers Predominated by Alternating Order: Theory and Application.
R. van Buel, D. Spitzer, C.M. Berač, P. van der Schoot, P. Besenius, Sara Jabbari-Farouji*,
J. Chem. Phys. 2019, 151, 014902. DOI: 10.1063/1.5097577.

[16] Structure and Luminescence Properties of Supramolecular Polymers of Amphiphilic Aromatic Thioether-Peptide Conjugates in Water.
P. Ahlers, C. Götz, S. Riebe, M. Zirbes, M. Jochem, D. Spitzer, J. Voskuhl*, T. Basché*, P. Besenius*,
Polym. Chem. 201910, 3163-3169. DOI: 10.1039/c8py01712c.

[15] Aqueous Supramolecular Polymers and Hydrogels.
D. Spitzer, P. Besenius,
in Supramolecular Chemistry in Water, ed.: S. Kubik, Wiley-VCH, Weinheim, 2019, 285-336. DOI: 10.1002/9783527814923.ch8.
Print ISBN: 9783527344673, online ISBN: 9783527814923 and DOI: 10.1002/9783527814923.

[14] A Clickable NHC-Au(I)-Complex for the Preparation of Stimulus-Responsive Metallopeptide Amphiphiles.
V. Lewe, M. Preuss, E.A. Woźnica, D. Spitzer, R. Otter, P. Besenius*,
Chem. Commun. 2018, 54, 9498-9501. DOI: 10.1039/c8cc05622f.

[13] Surface‐Assisted Self‐Assembly of a Hydrogel by Proton Diffusion.
D. Spitzer§, V. Marichez§, G.J.M.Formon, P.Besenius*, T.M.Hermans*,
Angew. Chem. 2018, 130, 11519-11523.  DOI: 10.1002/ange.201806668.
Angew. Chem. Int. Ed.
2018, 57, 11349-11353. DOI: 10.1002/anie.201806668.
(§ these authors contributed equally)

[12] Mannose-Decorated Multicomponent Supramolecular Polymers Trigger Effective Uptake into Antigen-Presenting Cells.
D. Straßburger, N. Stergiou, M. Urschbach, H. Yurugi, D. Spitzer, D. Schollmeyer, E. Schmitt*, P. Besenius*, ChemBioChem 201819, 912-916. DOI: 10.1002/cbic.201800114.

[11] Kinetically Controlled Stepwise Self-Assembly of Au(I)-Metallopeptides in Water.
B. Kemper, L. Zengerling, D. Spitzer, R. Otter, T. Bauer, P. Besenius*,
J. Am. Chem. Soc. 2018140, 534-537. DOI: 10.1021/jacs.7b08189.

[10] Folding Induced Supramolecular Assembly into pH-Responsive Nanorods with a Protein Repellent Shell.
R . Otter§, K. Klinker§, D. Spitzer, M. Schinnerer, M. Barz*, P. Besenius*,
Chem. Commun. 2018, 54, 401-404. DOI: 10.1039/c7cc08127h.
(§ these authors contributed equally)

[9] Tuneable Transient Thermogels Mediated by a pH- and Redox-Regulated Supramolecular Polimerization.
D. Spitzer, L.L. Rodrigues, D. Straßburger, M. Mezger, P. Besenius*,
Angew. Chem. 2017, 129, 15664-15669. DOI: 10.1002/ange.201708857.
Angew. Chem. Int. Ed.
2017, 56, 15461-15465. DOI: 10.1002/anie.201708857.

[8] Dynamic Light Scattering Investigation of the Kinetics and Fidelity of Supramolecular Copolymerizations in Water.
P. Ahlers, K. Fischer, D. Spitzer, P. Besenius*,
Macromolecules 2017, 50, 7712-7720. DOI: 10.1021/acs.macromol.7b01561.

[7] Tuning the pH-Switch of Supramolecular Polymer Carriers for siRNA to Physiologically Relevant pH.
P. Ahlers, H. Frisch, R. Holm, D. Spitzer, M. Barz, P. Besenius*,
Macromol. Biosci. 2017, 10, 1700111. DOI: 10.1002/mabi.201700111.

[6] Kinetic Control in the Temperature-Dependent Sequential Growth of Surface-Confined Supramolecular Copolymers.
S. Engel, D. Spitzer, L.L. Rodrigues, E.-C. Fritz, D. Straßburger, M. Schönhoff, B.J. Ravoo*, P. Besenius*,
Faraday Discuss. 2017, 204, 53-67. DOI: 10.1039/c7fd00100b.

[5] Reversible Covalent and Supramolecular Functionalization of Water-Soluble Au(I)-Complexes.
B. Kemper, M. von Gröning, V. Lewe, D. Spitzer, T. Otremba, N. Stergiou, D. Schollmeyer, E. Schmitt, B.J. Ravoo, P. Besenius*,
Chem. Eur. J. 2017, 23, 6048-6055. DOI: 10.1002/chem.201700588.

Graphical Abstract - ChemEurJ 2017 - Kemper

[4] Kinetically Controlled Sequential Growth of Surface-Grafted Chiral Supramolecular Copolymers.
H. Frisch§, E.-C. Fritz§, F. Stricker, L. Schmüser, D. Spitzer, T. Weidner, B.J. Ravoo*, P. Besenius*,
Angew. Chem. 2016128, 7358-7362. DOI: 10.1002/ange.201601048.
Angew. Chem. Int. Ed. 2016, 55, 7242-7246. DOI: 10.1002/anie.201601048.
(§ these authors contributed equally)

Graphical Abstract - ACIE 2016 - Frisch

[3] Probing the Self-Assembly and Stability of Oligohistidine based Rod-like Micelles by Aggregation Induced Luminescence.
H. Frisch, D. Spitzer, M. Haase, T. Basché, J. Voskuhl*, P. Besenius*,
Org. Biomol. Chem. 2016, 14, 5574-5579. DOI: 10.1039/c6ob00292g.

OBC 2016

[2] Side-Chain Effects on the Conductivity, Morphology, and Thermoelectric Properties of Self-Doped Narrow-Band-Gap Conjugated Polyelectrolytes.
C.-K. Mai, R.A. Schlitz, G.M. Su, D. Spitzer, X. Wang, S.L. Fronk, D.G. Cahill, M.L. Chabinyc, G.C. Bazan*,
J. Am. Chem. Soc. 2014, 136, 13478-13481. DOI: 10.1021/ja504284r.

Daniel Paper1

[1] The Synthesis of Dendritic EDOT-Peptide Conjugates and Their Multistimuli-Responsive Self-Assembly Into Supramolecular Nanorods and -Fibres in Water.
P. Ahlers, H. Frisch, D. Spitzer, Z. Vobecka, F. Vilela, P. Besenius*,
Chem. Asian J. 2014, 9, 2052–2057. DOI: 10.1002/asia.201402271.

Chem. Asian J. 2014, 9, 2052