Dr. Ronja Otter


Lab: 2224.02.125

Office: 2224.02.135

Phone: 39-23873



Research Topic:

Foldable supramolecular peptide-polymer conjugates

Curriculum Vitae:

07/2016 - 09/2019 Ph.D. student in the group of Prof. Pol Besenius, JGU Mainz
10/2018 - 11/2018 Research stay in the group of Prof. Subi George, JNCASR, Bangalore, India
12/2015 - 05/2016 Master thesis in the group of Prof. Pol Besenius, JGU Mainz
2014 - 2016 Master of Science in Biomedical Chemistry, JGU Mainz
2014 - 2015 DAAD-ISAP exchange student in the group of Prof. Gregory Tew,
University of Massachusetts, Amherst, USA
2014 Bachelor thesis in the group of Prof. Rudolf Zentel, JGU Mainz
2011 - 2014 Bachelor of Science in Biomedical Chemistry, JGU Mainz
2011 Abitur, Frauenlob-Gymnasium, Mainz



[11] Probing the Folding of Peptide-Polymer Conjugates Using the π-Dimerization of Viologen End-Groups.
R. Otter, P. Besenius*,
Organic Materials 20202, 143-148. DOI: 10.1055/s-0040-1710343.

[10] Impact of NDI-core Substitution on the pH-Responsive Nature of Peptide-Tethered Luminescent Supramolecular Polymers.
A. Sarkar, J. Kölsch, C.M. Berač, A. Venugopal, R. Sasmal, R. Otter, P. Besenius*, S.J. George*,
ChemistryOpen 2020, 9, 346-350. DOI: 10.1002/open.202000017.

[9] Evaluation of Charge-Regulated Supramolecular Copolymerization to Tune the Time-Scale for Oxidative Disassembly of ß-Sheet Comonomers.
C.M. Berač, L. Zengerling, D. Straßburger, R. Otter, M. Urschbach, P. Besenius*,
Macromol. Rapid Commun. 2019, 1900476, DOI: 10.1002/marc.201900476.

[8] Supramolecular Assembly of Functional Peptide-Polymer Conjugates.
R. Otter, P. Besenius*,
Org. Biomol. Chem. 2019, 17, 6719-6734. DOI: 10.1039/c9ob01191a.

[7] Tuning the Life-Time of Supramolecular Hydrogels using ROS-Responsive Telechelic Peptide-Polymer Conjugates.
R. Otter, C. Berač, S. Seiffert, P. Besenius*,
Eur. Polym. J. 2019, 110, 90-96. DOI: 10.1016/j.eurpolymj.2018.11.019.

[6] A Clickable NHC-Au(I)-Complex for the Preparation of Stimulus-Responsive Metallopeptide Amphiphiles.
V. Lewe, M. Preuss, E.A. Woźnica, D. Spitzer, R. Otter, P. Besenius*,
Chem. Commun. 2018, 54, 9498-9501. DOI: 10.1039/c8cc05622f.

[5] Secondary Structure-Driven Hydrogelation using Foldable Telechelic Polymer-Peptide Conjugates.
R. Otter, N.A. Henke, C. Berač, T. Bauer, M. Barz, S. Seiffert, P. Besenius*,
Macromol. Rapid Commun. 2018, 39, 1800459. DOI: 10.1002/marc.201800459.

[4] Kinetically Controlled Stepwise Self-Assembly of Au(I)-Metallopeptides in Water.
B. Kemper, L. Zengerling, D. Spitzer, R. Otter, T. Bauer, P. Besenius*,
J. Am. Chem. Soc. 2018140, 534-537. DOI: 10.1021/jacs.7b08189.

[3] Folding Induced Supramolecular Assembly into pH-Responsive Nanorods with a Protein Repellent Shell.
R. Otter§, K. Klinker§, D. Spitzer, M. Schinnerer, M. Barz*, P. Besenius*,
Chem. Commun. 2018, 54, 401-404. DOI: 10.1039/c7cc08127h.                                                                       (§ these authors contributed equally)

[2] Increased hydrophobic block length of PTDMs promotes protein internalization.
C. M. Backlund, F. Sgolastra, R. Otter, L. M. Minter, T. Takeuchi, S. Futakid and G. N. Tew*,
Polym. Chem. 2016, 7, 7514-7521. DOI: 10.1039/C6PY01615D.

[1] Optimal Hydrophobicity in Ring-Opening Metathesis Polymerization-Based Protein Mimics Required for siRNA Internalization.
B. M. deRonde, N. D. Posey, R. Otter, L. M. Caffrey, L. M. Minter, G. N. Tew*,
Biomacromolecules 2016, 17, 1969-1977. DOI: 10.1021/acs.biomac.6b00138.