Dr. David Straßburger


Lab: 2224.02.131

Office: 2224.02.135

Phone: 39-23873

Mail: dastrass@uni-mainz.de


Research Topic:

Nanoscaled supramolecular peptide-glycopeptide conjugate vaccines

Curriculum Vitae:

11/2015 - 10/2018 Ph.D. student in the group of Prof. Pol Besenius, JGU Mainz
03/2015 - 10/2015 Master thesis in the group of Prof. Horst Kunz, JGU Mainz
Topic: synthetic glycopeptide vaccines
04/2014 - 10/2015 Master of Science in Biomedical Chemistry, JGU Mainz
08/2013 - 04/2014 DAAD-ISAP exchange student in the group of Prof. Gregory Tew,
University of Massachusetts, Amherst, USA
Topic: metal-containing polymers
08/2013 Bachelor thesis in the group of Prof. Horst Kunz, JGU Mainz
2010 - 2013 Bachelor of Science in Biomedical Chemistry, JGU Mainz
06/2010 - 10/2010 Research Internship, Boehringer Ingelheim RCV GmbH & Co KG, Vienna
09/2007 - 06/2010 Apprenticeship as lab assistant, Boehringer Ingelheim Pharma GmbH & Co KG, Ingelheim
2007 Abitur, Stefan George-Gymnasium, Bingen



[6] Evaluation of Charge-Regulated Supramolecular Copolymerization to Tune the Time-Scale for Oxidative Disassembly of ß-Sheet Comonomers.
C.M. Berač, L. Zengerling, D. Straßburger, R. Otter, M. Urschbach, P. Besenius*,
Macromol. Rapid Commun. 2019, 1900476, DOI: 10.1002/marc.201900476.

[5] Synthetic MUC1 Antitumor Vaccine with Incorporated 2,3-Sialyl-T Carbohydrate Antigen Inducing Strong Immune Responses with Isotype Specificity.
D. Straßburger, M. Glaffig, N. Stergiou, S. Bialas, P. Besenius, E. Schmitt, H. Kunz*
ChemBioChem 201819, in press. DOI: 10.1002/cbic.201800148.

[4] Mannose-Decorated Multicomponent Supramolecular Polymers Trigger Effective Uptake into Antigen-Presenting Cells.
D. Straßburger, N. Stergiou, M. Urschbach, H. Yurugi, D. Spitzer, D. Schollmeyer, E. Schmitt*, P. Besenius*, ChemBioChem 201819, 912-916. DOI: 10.1002/cbic.201800114.
Cover Feature: ChemBioChem 2018, 19, 894. DOI: 10.1002/cbic.201800191.

[3] Tuneable Transient Thermogels Mediated by a pH- and Redox-Regulated Supramolecular Polimerization.
D. Spitzer, L.L. Rodrigues, D. Straßburger, M. Mezger, P. Besenius*,
Angew. Chem. 2017, 129, 15664-15669. DOI: 10.1002/ange.201708857.
Angew. Chem. Int. Ed.
2017, 56, 15461-15465. DOI: 10.1002/anie.201708857.

[2] Kinetic Control in the Temperature-Dependent Sequential Growth of Surface-Confined Supramolecular Copolymers.
S. Engel, D. Spitzer, L.L. Rodrigues, E.-C. Fritz, D. Straßburger, M. Schönhoff, B.J. Ravoo*, P. Besenius*,
Faraday Discuss. 2017, 204, 53-67. DOI: 10.1039/c7fd00100b.

[1] Enhanced immunogenicity of multivalent MUC1 glycopeptide antitumour vaccines based on hyperbranched polymers.
M. Glaffig, B. Palitzsch, N. Stergiou, C. Schüll, D. Straßburger, E. Schmitt, H. Frey, H. Kunz*,
Org. Biomol. Chem., 2015, 13, 10150-10154. DOI: 10.1039/c5ob01255d.

Chem. Asian J. 2014, 9, 2052