Complex (Supra)Molecular Systems – SoSe 2023

 

The lecture is a joint class between Jun.-Prof. Shikha Dhiman, Prof. Pol Besenius and Prof. Andreas Walther. It is part of the focus 'Macromolecular Chemistry' in the MSc Chemistry and is offered as an elective module in the MSc Biomedical Chemistry. It provides an in-depth insight into the structure, dynamics and characterisation of supramolecular structures based on (bio)organic components and (bio)macromolecules. The goal is to cover recognition motifs, weak non-covalent interactions, and principles of self-assembly and self-organization in natural and synthetic systems. Biological and chemical reaction networks and their dynamics are discussed, as well as the difference between equilibrium and nonequilibrium systems. The fundamentals of DNA Nanoscience, Systems Chemistry and concepts for Adaptive and Interactive Material Systems will be finally presented and discussed.

Registration is in JOGU-StINe (the final registration period ends at 21:00 on 21/4/2023). The lecture will be held on Tuesdays from 10:00-12:00 in the seminar room 00.210 PC1 (starting April 25). Lecture materials will be made available via the Moodle LMS.

The lecture contents are as follows:

  1. Introduction (PB)
  2. Binding forces (PB)
  3. Supramolecular polymerization
    part 1 – thermodynamics, design principles and applications (PB)
  4. Peptide and protein nanotechnology – kinetics and pathway complexity (PB)
  5. Supramolecular polymerization
    part 2 – kinetics, pathway complexity and autocatalysis (PB)
  6. Dynamic combinatorial chemistry (PB)
  7. Characterisation of supramolecular complex systems – part 1 (SD)
  8. Characterisation of supramolecular complex systems – part 2 (SD)
  9. Structural DNA nanoscience (AW)
  10. Dynamic DNA nanoscience (AW)
  11. Life-Like Systems and Materials Systems:
    Chemical Reaction Networks and Systems Chemistry – part 1 (AW)
  12. Life-Like Systems and Materials Systems:
    Chemical Reaction Networks and Systems Chemistry – part 1 (AW)